| 摘要 |
Provided are anti-wrinkle agents having a novel parent nucleus that are suitable as components for external skin preparations such as cosmetics. The anti-wrinkle agents comprise compounds represented by general formula (1), stereoisomers thereof, or pharmacologically permissible salts thereof. Said anti-wrinkle agents have excellent efficacy in improving wrinkles and sagging that occur as a result of photoaging due to ultraviolet ray exposure that is skin aging with increased age. [In the formula, R1 represents a hydrogen atom or a 1- to 8-carbon straight or branched alkyl group. R2 represents -SH, -SO3H, SSX1, SX2, SOX3, SO2X4, SO2NY1X5 or SO2NY2Y3. X1-X5 independently are hydrogen atoms or 1- to 8-carbon aliphatic hydrocarbon groups or 5- to 12-carbon aromatic parts wherein carbon atoms may be substituted with heteroatoms. Y1-Y3 independently represent hydrogen atoms or 1- to 8-carbon straight or branched alkyl groups. R3 represents a hydrogen atom or acyl group having a 1- to 8-carbon straight or branched alkyl chain. R4 represents a 5- to 12-carbon aromatic group or polycyclic condensed aromatic group that may have unsubstituted or substituted groups. m represents an integer 0-3 and n represents an integer 1 or 2.] |
