The present invention relates to a method for determining the risk of a pregnant woman developing pre-eclampsia. The method comprises i) determining the level of one or more biochemical markers in a sample obtained from a pregnant woman, and ii) comparing the level of the at least one biochemical marker in the sample with the level of the same biochemical marker in a control sample. A difference in the level of the biochemical marker in the sample relative to the control sample is indicative of an increased risk of developing pre-eclampsia. The isoform biochemical markers are preferably PlGF-2 and PlGF-3. The present invention relates also to a method for determining whether a pregnant woman has pre-eclampsia and as well as a kit for assessing the risk or presence of pre-eclampsia. In addition, the invention relates also to a computer program used in these determinations.
申请公布号
CA2743570(A1)
申请公布日期
2010.05.27
申请号
CA20092743570
申请日期
2009.11.20
申请人
PERKINELMER HEALTH SCIENCES, INC.;NTD LABORATORIES, INC.;WALLAC OY
发明人
AHOLA, TARJA;FRANG, HEINI;KORPIMAEKI, TEEMU;HURSKAINEN, PERTTI;BOBROW, MARK N.;CARMICHAEL, JONATHAN B.