发明名称 |
BLADDER CANCER TREATMENT INCLUDING DECISION AT TUMOR ENZYME LEVEL |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a treatment for individually targeted bladder cancer by taking advantage of propylene glycol concentrations and/or NAD(P)H:quinone oxidoreductase-1 (NQO1), Cytochrome P450 Oxidoreductase (P450R) and Glucose transporter 1 (Glut-1) protein expressions in human bladder transitional cell carcinoma. Ž<P>SOLUTION: A method of treating bladder cancers includes a step of deciding a level of at least one enzyme in a tumor, a step of selecting a treatment based on the level of the at least one enzyme, and a step of giving the treatment; the treatment includes administration of a quinone-based intravital reductive medicament alone or in combination with another treatment. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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申请公布号 |
JP2010116416(A) |
申请公布日期 |
2010.05.27 |
申请号 |
JP20100022599 |
申请日期 |
2010.02.03 |
申请人 |
SPECTRUM PHARMACEUTICALS INC;UNIV OF BRADFORD |
发明人 |
PHILLIPS ROGER M;LENAZ LUIGI |
分类号 |
A61K45/00;A61K31/404;A61K45/06;A61P35/00 |
主分类号 |
A61K45/00 |
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地址 |
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