发明名称 METHOD OF DETERMINING USE OF ERYTHROPOETIN DURING DOPING TESTS IN ATHLETES
摘要 FIELD: chemistry. ^ SUBSTANCE: risk group is made first. Urine samples of athletes undergo high performance liquid chromatography coupled with tandem mass spectrometry. Content of indirect biochemical markers - L-arginine, asymmetrical dimethylarginine, symmetrical dimethylarginine and citrulline is determined. If content of the defined products in the sample is not within 0.9-1.2 of the averaged standard, the athlete is removed from the risk group. If content of the said products is at least greater than 1.5 times the averaged standard, the athlete is included in the risk group. The urine sample of the said athlete is subjected to isoelectric fixation, double blotting and chemoluminescent analysis for exogenous erythropoietin. ^ EFFECT: method cuts the time for testing a group of athletes for doping and expenses for carrying out analysis. ^ 3 tbl, 4 ex
申请公布号 RU2390779(C2) 申请公布日期 2010.05.27
申请号 RU20080127780 申请日期 2008.07.10
申请人 FEDERAL'NOE GOSUDARSTVENNOE UNITARNOE PREDPRIJATIE "ANTIDOPINGOVYJ TSENTR" 发明人 APPOLONOVA SVETLANA ALEKSANDROVNA;DIKUNETS MARINA ALEKSANDROVNA;RODCHENKOV GRIGORIJ MIKHAJLOVICH
分类号 G01N21/00;G01N30/00;G01N33/493 主分类号 G01N21/00
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