<p>A cell culture medium and system are provided which eliminates or at least reduces the need for feeder cells. The cell culture medium comprises one or more factors that are normally secreted and/or produced by a feeder cell and a synthetic chimeric protein comprising IGF-I and a portion of vitronectin. The cell culture medium is particularly suitable for propagating human embryonic stem cells and keratinocytes. This invention also relates to compositions and methods which utilize the cells cultured in the cell culture medium of the invention.</p>
申请公布号
EP2188369(A1)
申请公布日期
2010.05.26
申请号
EP20080799972
申请日期
2008.09.03
申请人
QUEENSLAND UNIVERSITY OF TECHNOLOGY
发明人
UPTON, ZEE;LEAVESLEY, DAVID;RICHARDS, SEAN DENNIS;CORMACK, LUKE BRYANT;HARKIN, DAMIEN