发明名称 |
COMPOSITION CONTAINING MICRORNA-21 INHIBITOR FOR ENHANCING RADIATION SENSITIVITY |
摘要 |
<p>Disclosed is a radiation sensitivity-enhancing composition in which a microRNA-21 inhibitor acts as an active ingredient. The microRNA-21 inhibitor is an antisense nucleic acid molecule binding complementarily to microRNA-21. The composition can be administered to a patient in conjunction with irradiation. The inhibitor can act as a radiosensitizer, enhancing the therapeutic effect of such irradiation on cancer high in microRNA-21 expression level, particularly, glioma.</p> |
申请公布号 |
EP2187895(A1) |
申请公布日期 |
2010.05.26 |
申请号 |
EP20080778956 |
申请日期 |
2008.07.30 |
申请人 |
NATIONAL CANCER CENTER |
发明人 |
PARK, JONG BAE;LEE, SEUNG HOON;KWAK, HEE JIN;KIM, TAE HOON;YOO, HEON;LEE, DONGHEE;PARK, EUN KYOUNG;KIM, HEA JIN |
分类号 |
A61K31/7105;A61K31/00;A61K41/00;A61P35/00;C12N15/113 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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