| 发明名称 |
Human anti-folate receptor alpha antibodies and antibody fragments for the radioimmunotherapy of ovarian carcinoma |
| 摘要 |
Antibody or fragment thereof, which specifically binds to folate receptor-alpha (FR±), wherein said antibody or fragment thereof comprises a light chain whose variable region comprises at least one of the following amino acid sequences :
- RASESVSFLGINLIH (SEQ ID NO: 3),
- QASNKDT (SEQ ID NO: 4),
- LQSKNFPPYT (SEQ ID NO: 5),
and wherein the constant region of said light chain is a kappa constant region. |
| 申请公布号 |
ZA200901328(B) |
申请公布日期 |
2010.05.26 |
| 申请号 |
ZA20090001328 |
申请日期 |
2007.09.12 |
| 申请人 |
DOMPE PHA.R.MA S.P.A;ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI |
发明人 |
MARTIN, FRANCK;CATTOZZO, MARGHERITA;DI CIOCCIO VITO;MAURIZI, GIOVANNI;FIGINI, MARIANGELA;CANEVARI, SILVANA |
| 分类号 |
C07K |
主分类号 |
C07K |
| 代理机构 |
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