Bicyclic peptidomimetic inhibitors of aspartyl-proteases for the treatment of infectious diseases
摘要
The present invention refers to 3-aza-bicyclo[3.2.1 ]octane derivatives of general formula (I) their preparation, use and pharmaceutical compositions useful in the treatment of pathologies associated with microbial pathogens expressing aspartyl-protease activity.
申请公布号
EP2189462(A1)
申请公布日期
2010.05.26
申请号
EP20080169901
申请日期
2008.11.25
申请人
UNIVERSITA' DEGLI STUDI DI FIRENZE;INSTITUTO SUPERIORE DI SANITA'
发明人
CASSONE, ANTONIO;DE BERNARDIS, FLAVIA;GARACI, ENRICO;TRABOCCHI, ANDREA;GUARNA, ANTONIO
