发明名称 |
Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith |
摘要 |
Provided herein are Aminopurine Compounds having the following structure: wherein R1, R2 and and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
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申请公布号 |
US7723340(B2) |
申请公布日期 |
2010.05.25 |
申请号 |
US20060332617 |
申请日期 |
2006.01.12 |
申请人 |
SIGNAL PHARMACEUTICALS, LLC;PHARMACOPEIA DRUG DISCOVERY, INC. |
发明人 |
ALBERS RONALD J.;AYALA LETICIA;CLAREEN STEVEN S.;DELGADO MEDEROS MARIA MERCEDES;HILGRAF ROBERT;HEGDE SAYEE G.;HUGHES KEVIN;KOIS ADAM;PLANTEVIN-KRENITSKY VERONIQUE;MCCARRICK MEG;NADOLNY LISA;PALANKI MOORTHY S. S.;SAHASRABUDHE KIRAN;SAPIENZA JOHN;SATOH YOSHITAKA;SLOSS MARIANNE K.;SUDBECK ELISE;WRIGHT JONATHAN;HENDERSON IAN;COLE ANDREW G. |
分类号 |
C07D473/32;A61F2/82;A61K31/52;A61P3/10;A61P11/00;C07D239/48;C07D239/50 |
主分类号 |
C07D473/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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