发明名称 Process for preparing organic compounds
摘要 Process for preparing a compound of the formula (I) in which R1 and R2 are each independently H, C1-C8-alkyl, halogen, polyhalo-C1-C8-alkoxy, polyhalo-C1-C8-alkyl, C1-C8-alkoxy, C1-C8-alkoxy-C1-C8-alkyl, or C1-C8-alkoxy-C1-C8-alkoxy, where R1 and R2 are not both H, and R3 is C1-C8-alkyl, which is characterized in that a) a compound of the formula (II) in which R1 and R2 are each as defined above and X is Br, I, triflate, toyslate or mesylate is reacted with prop-2-yn-1-ol to give the compound of the formula (III), b) the compound of the formula (III) is reacted with an alkyl-metal compound in which “alkyl” is as defined above for R3 to give a compound of the formula (I).
申请公布号 US7723550(B2) 申请公布日期 2010.05.25
申请号 US20070224418 申请日期 2007.11.08
申请人 NOVARTIS AG 发明人 HEROLD PETER;MAH ROBERT;STUTZ STEFAN;STOJANOVIC ALEKSANDAR;LYOTHIER ISABELLE;BEHNKE DIRK
分类号 C07C29/36;C07C29/44;C07C41/18;C07C41/30;C07C43/23 主分类号 C07C29/36
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