发明名称 |
RNAi modulation of ApoB and uses thereof |
摘要 |
The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides. |
申请公布号 |
US7723317(B2) |
申请公布日期 |
2010.05.25 |
申请号 |
US20090400744 |
申请日期 |
2009.03.09 |
申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
SOUTSCHEK JUERGEN;VORNLOCHER HANS-PETER;HADWIGER PHILIPP;ELBASHIR SAYDA |
分类号 |
C07H21/02;C07H21/04;C12Q1/68 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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