CHIRAL AMINE-(SULPHUR) UREA DOUBLE FUNCTIONAL CATALYST AND SYNTHESIS METHOD AND USE THEREOF

摘要

A chiral amino- (thio) carbamide dual function tructural formulas (S, R) or (R, S) wherein R1 is hydrogen, a nitro group, alkylsulfonyl group, alkylsulfinyl group, cyano group, halogen or C1-C4 alkoxy group; R2 and R3 are hydrogen, C1-C6 straight chain or branched alkyl groups, C3-C8 cycloalkyl groups, C2-C6 alkenyl groups, C2-C6 alkynyl groups, aralkyl groups or aralkenyl groups; R4 is a C1-C4 alkylsilyl group, arylsilyl group, aralkylsilyl group, C1-C6 alkyl group, substituted alkyl group, aralkyl group, C2-C6 alkenyl group or C2-C6 alkynyl group; R5 is a C3-C8 cycloalkyl group, C1-C6 alkylsulfinyl group, heterocyclic group, aryl group or R6 or/and R7-substituted aryl group, where the said R6 or R7 substituent is a perfluoro C1-C4 alkyl group, C1-C4 alkoxy group, halogen, nitro group, alkyl-acyl group, alkylsulfonyl or alkylsulfinyl group; and X is sulfur or oxygen.