METHODS OF INHIBITING CANCER CELL GROWTH WITH HDAC INHIBITORS AND METHODS OF SCREENING FOR HDAC10 INHIBITORS
摘要
<p>Methods of inhibiting cancer cell growth using HDAC10 inhibitors are provided. Methods of treating cancer in a subject using HDAC10 inhibitors are also provided. In certain embodiments, at least one second inhibitor selected from an autophagy inhibitor, an AMPK inhibitor, and methylpyruvate is also used in the methods. Dose packs comprising HDAC10 inhibitors and at least one second inhibitor are provided. Methods of identifying HDAC10 inhibitors are also provided.</p>
申请公布号
WO2010056677(A1)
申请公布日期
2010.05.20
申请号
WO2009US63905
申请日期
2009.11.10
申请人
DUKE UNIVERSITY;YAO, TSO-PANG;SASAJIMA, HITOSHI;KAWAGUCHI, YOSHIHARU;CUI, KAI;LAI, CHUN-HSIANG