METHODS FOR PURIFICATION OF SINGLE DOMAIN ANTIGEN BINDING MOLECULES
摘要
Processes and methods of purifying or separating single domain antigen binding (SDAB) molecules that include one or more single binding domains (e.g., one or more nanobody molecules), substantially devoid of a complementary antibody domain and an immunoglobulin constant region, using Protein A-based affinity chromatography, are disclosed.
申请公布号
WO2010056550(A1)
申请公布日期
2010.05.20
申请号
WO2009US62651
申请日期
2009.10.29
申请人
WYETH LLC;BROWN, PAUL, R.;TOBLER, SCOTT, ANDREAS;WOOD, ANDREW, M.;BOESCH, AUSTIN, WAYNE
发明人
BROWN, PAUL, R.;TOBLER, SCOTT, ANDREAS;WOOD, ANDREW, M.;BOESCH, AUSTIN, WAYNE