6-PHENYL-1H-IMIDAZOÄ4, 5-CÜPYRIDIN-4-CARBONITRIL-DERIVATE ALS CATHEPSIN-K- UND -S-HEMMER

摘要

The present invention relates to 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives having the general Formula (I), to pharmaceutical compositions comprising the same as well as to the use of these derivatives for the preparation of a medicament for the treatment of cathepsin S and/or cathepsin K related diseases such as osteoporosis, atherosclerosis, inflammation and immune disorders, such as rheumatoid arthritis, and chronic pain, such as neuropathic pain.