发明名称 |
MEDICINE CONTAINING DOPAMINE D2-LIKE RECEPTOR AGONIST AS ACTIVE INGREDIENT AND SCREENING METHOD |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a medicine effective for a disease (e.g. multiple sclerosis) caused by the excessive reaction of Th2 or Th17 of a helper T cell, and to provide an effective screening method of the medicine. <P>SOLUTION: The medicine for treating or preventing the disease caused by the excessive reaction of the Th2 or the Th17 contains a dopamine D2-like receptor agonist as an active ingredient. The screening method of the medicine uses the bond to the dopamine D2-like receptor and/or the active effect on the dopamine D2-like receptor as an indicator. Especially, at least one of pramipexole hydrochloride hydrate and ropinirole hydrochloride is preferable as the medicine. <P>COPYRIGHT: (C)2010,JPO&INPIT |
申请公布号 |
JP2010111581(A) |
申请公布日期 |
2010.05.20 |
申请号 |
JP20070014786 |
申请日期 |
2007.01.25 |
申请人 |
IMUNO:KK;SAITAMA MEDICAL UNIV |
发明人 |
MATSUSHITA SHO;NAKANO KAZUHISA |
分类号 |
A61K45/00;A61K31/4045;A61K31/428;A61P3/10;A61P11/06;A61P13/12;A61P17/00;A61P19/02;A61P21/00;A61P25/00;A61P29/00;A61P37/06;A61P37/08;A61P43/00;G01N33/15;G01N33/50 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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