发明名称 |
CD37 IMMUNOTHERAPEUTIC COMBINATION THERAPIES AND USES THEREOF |
摘要 |
<p>The present disclosure provides methods for using CD37-specific binding molecules (such as a CD37-specific SMIP or antibody) in combination with mTOR inhibitors (such as rapamycin and derivatives or analogues thereof) or phosphatidylinositol 3-kinase (PI3K) inhibitors (such as p110?-specific inhibitors or the like), which can be done concurrently or sequentially, to treat or prevent a B cell related hyperproliferative disease, such as a lymphoma, carcinoma, myeloma, or the like.</p> |
申请公布号 |
WO2010057047(A1) |
申请公布日期 |
2010.05.20 |
申请号 |
WO2009US64470 |
申请日期 |
2009.11.13 |
申请人 |
TRUBION PHARMACEUTICS, INC.;CERVENY, CHARLES, G.;THOMPSON, PETER, A. |
发明人 |
CERVENY, CHARLES, G.;THOMPSON, PETER, A. |
分类号 |
A61K39/395;A61K31/436;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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