ENANTIOMERENREINE AMINOHETEROARYL-VERBINDUNGEN ALS PROTEINKINASEHEMMER
摘要
Enantiomerically pure compound of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.
申请公布号
DE602005020465(D1)
申请公布日期
2010.05.20
申请号
DE20056020465T
申请日期
2005.08.15
申请人
PFIZER INC.
发明人
CUI, JINGRONG J.;FUNK, LEE A.;JIA, LEI;KUNG, PEI-PEI;MENG, JERRY J.;NAMBU, MITCHELL D.;PAIRISH, MASON A.;TRAN-DUBE, M. B.