发明名称 |
ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME IN COMBINATION WITH BLOOD COAGULATING AGENTS |
摘要 |
The present invention relates to antidotes of anticoagulants targeting factor Xa which antidotes are used in combination with blood coagulating agents or other heparin antidotes to prevent or reduce bleeding in a subject. The antidotes described herein have reduced or no intrinsic coagulant activity. Disclosed herein are methods of stopping or preventing bleeding in a patient that is or will be undergoing anticoagulant therapy with a factor Xa inhibitor.
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申请公布号 |
US2010125052(A1) |
申请公布日期 |
2010.05.20 |
申请号 |
US20090616735 |
申请日期 |
2009.11.11 |
申请人 |
PORTOLA PHARMACEUTICALS, INC. |
发明人 |
LU GENMIN;SINHA UMA |
分类号 |
A61K38/36;A61P7/00 |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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