发明名称 |
ANTI-HUMAN IL-21 MONOCLONAL ANTIBODIES |
摘要 |
<p>Human anti-human IL-21 monoclonal antibodies and the hybridomas that produce them are presented. Certain of these antibodies have the ability to bind native human IL-21, a mutant recombinat IL-21 protein and/or peptide regions of human IL-21. These human anti-IL-21 antibodies are useful in therapeutic treatment of autoimmune and inflammatory diseases, particularly diseases mediated by T follicular helper cells, B cells T H cells or T H17 cells.</p> |
申请公布号 |
CA2910933(A1) |
申请公布日期 |
2010.05.20 |
申请号 |
CA20082910933 |
申请日期 |
2008.12.08 |
申请人 |
ZYMOGENETICS, INC. |
发明人 |
JASPERS, STEPHEN R.;RIXON, MARK W.;DILLON, STACEY R.;RANSDELL, FREDERICK J.;KREJSA, CECILE M.;YI, EUGENE C. |
分类号 |
C07K16/24;A61K39/395;A61P1/00;A61P3/10;A61P17/06;A61P19/02;A61P37/06;C12N5/16;C12P21/08 |
主分类号 |
C07K16/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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