发明名称 1,5,6-SUBSTITUTED 2-OXO-3-CYANO-1,6A-DIAZATETRAHYDROFLUORANTHENES
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to new compounds of formula , to their salts, where R1 and R2 each independently is hydrogen or C1-10alkyl which can be optionally substituted with substitutes selected from a group comprising a hydroxyl group, NR4R5, pyrrolidinyl, piperidinyl, morpholinyl; R3 is a radical of formula , where n equals 1; R3a is nitro; X is -NR7 - or -O-; R4 and R5 each independently is C1-6alkyl; R7 is hydrogen, C1-6alkyl, optionally substituted with pyrrolidinyl. The invention also pertains to use of the compounds, to a pharmaceutical composition, to a method of preparing the pharmaceutical composition, as well as to a method of obtaining the chemical compound in any of paragraphs 1-3. ^ EFFECT: obtaining new biologically active compounds with antiviral activity. ^ 7 cl, 4 ex, 2 tbl
申请公布号 RU2389730(C2) 申请公布日期 2010.05.20
申请号 RU20070130550 申请日期 2006.01.10
申请人 TIBOTEK FARMAS'JUTIKALZ LTD. 发明人 KESTELEJN BART RUDOL'F ROMANI;RABUASSON P'ER ZHAN-MARI;VAN DE FREJKEN VIM;KANAR MAKSIM FRANSIS ZHAN-MARI GILEHJN
分类号 A61K31/4985;A61P31/18;C07D471/16;C07D498/16 主分类号 A61K31/4985
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