发明名称 METHODS FOR BONE CANCER RELATED PAIN MANAGEMENT BY ADMINISTRATION OF NERVE GROWTH FACTOR ANTAGONIST
摘要 FIELD: medicine. ^ SUBSTANCE: group of the inventions refers to medicine, namely to oncology, and can be used in bone cancer related pain management. The method involves administration to the patient of effective amount of a nerve growth factor (NGF) antagonist representing a NGF antibody. A set includes the NGF antagonist in the form of the NGF antibody and application instructions. ^ EFFECT: inventions allow for effective pain management, both constant, and motion related, due to high affinity of the NGF antibody without affecting the initial thresholds of thermal and mechanical sensitivity. ^ 20 cl, 4 tbl, 14 dwg, 4 ex
申请公布号 RU2389509(C2) 申请公布日期 2010.05.20
申请号 RU20060139073 申请日期 2005.04.07
申请人 RINAT N'JUROSAJENS KORP.;RIDZHENTS OF DZE JUNIVERSITI OF MINNESOTA 发明人 SHELTON DEHVID L.;MANTIKH PATRIK UILL'JAM
分类号 A61K39/395;A61P23/00;C07K16/00;C07K16/22 主分类号 A61K39/395
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