| 发明名称 |
3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL COA DESATURASE INHIBITORS |
| 摘要 |
The present invention discloses 3-hydroquinazolm-4-one derivatives for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cancer, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
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| 申请公布号 |
CA2740389(A1) |
申请公布日期 |
2010.05.20 |
| 申请号 |
CA20082740389 |
申请日期 |
2008.10.15 |
| 申请人 |
GILEAD SCIENCES, INC. |
发明人 |
KOLTUN, DMITRY;PARKHILL, ERIC;BOZE, MELANIE;ZABLOCKI, JEFF;VASILEVICH, NATALYA;MAYBORODA, ELENA;GLUSHKOV, ANDREY;COLE, ANDREW;CHISHOLM, JEFFREY |
| 分类号 |
C07D239/91;A61K31/517;A61P3/00;C07D471/04 |
主分类号 |
C07D239/91 |
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