发明名称 |
POWDER FORMATION BY ATMOSPHERIC SPRAY-FREEZE DRYING |
摘要 |
A method of manufacturing heat-sensitive pharmaceutical powder is disclosed. The original pharmaceutical substances are dissolved in a solution or suspended in a suspension, which is sprayed through an atomizing nozzle and frozen in a cold gas phase or liquid nitrogen atomized directly in the spray-freeze chamber or gas jacket at the same time (for cooling purposes). The particles are freeze-dried at roughly atmospheric pressure in a down-stream fluid flow with exit filter thereby to remove moisture entrapped on or inside the frozen particles. The system has applicability for forming other powders. |
申请公布号 |
EP1697035(A4) |
申请公布日期 |
2010.05.19 |
申请号 |
EP20040802335 |
申请日期 |
2004.12.20 |
申请人 |
FINLAY, WARREN H.;WANG, ZHILIN |
发明人 |
FINLAY, WARREN H.;WANG, ZHILIN |
分类号 |
B01J2/04;A61J3/02;A61K9/14;A61K9/19;F26B5/06 |
主分类号 |
B01J2/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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