发明名称 Non-immunogenic, hydrophilic/cationic block copolymers and uses thereof
摘要 The present invention provides novel non-immunogenic, hydrophilic/cationic block copolymers comprising a neutral-hydrophilic polymer and a cationic polymer, wherein both polymers have well-defined chain-end functionality. A representative example of such a block copolymer comprises poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly(N-[3-(dimethylamino)propyl]methacrylamide) (PDMAPMA). Also provided is a synthesis method thereof in aqueous media via reversible addition fragmentation chain transfer (RAFT) polymerization. Further provided are uses of these block copolymers as drug delivery vehicles and protection agents.
申请公布号 US7718432(B2) 申请公布日期 2010.05.18
申请号 US20070725964 申请日期 2007.03.20
申请人 THE UNIVERSITY OF SOUTHERN MISSISSIPPI 发明人 SCALES CHARLES W.;HUANG FAQING;MCCORMICK CHARLES L.
分类号 C12N15/63;C07H21/04;C08F2/00;C12Q1/68 主分类号 C12N15/63
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