FUS/TLS-BASED COMPOUNDS AND METHODS FOR DIAGNOSIS, TREATMENT AND PREVENTION OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED MOTOR NEURON DISEASES
摘要
The invention provides novel FUS/TLS nucleic acids and proteins that comprise one or more genetic markers (for example, single nucleotide polymorphisms) and methods of use thereof including methods relating to the diagnosis of ALS or other related motor neuron disease by virtue of the presence of the mutant FUS/TLS sequence(s).
申请公布号
WO2010011283(A3)
申请公布日期
2010.05.14
申请号
WO2009US04205
申请日期
2009.07.21
申请人
THE GENERAL HOSPITAL CORPORATION;KWIATKOWSKI, THOMAS, J.;BROWN, ROBERT, H.