PIRFENIDONE TREATMENT FOR PATIENTS WITH ATYPICAL LIVER FUNCTION
摘要
Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone administration. The methods include administering to a patient pirfenidone at doses lower than the full target dosage for a time period, followed by administering to the patient pirfenidone at the full target dosage. The methods also include administering pirfenidone at the full target dose with no reduction and administering permanently reduced doses of pirfenidone.
申请公布号
WO2010054294(A1)
申请公布日期
2010.05.14
申请号
WO2009US63702
申请日期
2009.11.09
申请人
INTERMUNE, INC.;BRADFORD, WILLIAMSON, ZIEGLER;SZWARCBERG, JAVIER