METHOD FOR DELIVERING CARGOES INTO CELLS, AND PEPTIDE FOR SAME

摘要

The present invention provides a peptide for delivering cargoes into cells, wherein the peptide contains an intracellular transduction domain. Said intracellular transduction domain is a peptide containing a hydrophilic domain for improving the interaction between charged materials and/or the solubility of the intracellular transduction domain and the cargoes, and a hydrophobic domain which can be used in a hydrophobic interaction and/or an interaction with cell membranes. Said intracellular transduction domain delivers the cargoes into cells when the intracellular transduction domain is not conjugated to the cargoes. The present invention provides a method for delivering cargoes into cells that comprises the steps of preparing an intracellular transduction domain, preparing cargoes to be delivered into cells, treating cells with the cargoes and the intracellular transduction domain when the cargoes and the intracellular transduction domains are not conjugated to each other, and delivering the cargoes into cells.