发明名称 |
Peptides Having Activities of Epidermal Growth Factor and Its Uses |
摘要 |
The present invention relates to peptides comprising the amino acid sequence represented by the following formula 1 and having the activities of epidermal growth factor and their uses: Cys-Met-Tyr-Ile-Glu-Linker-Arg-Gly-Asp (1) The EGF-mimicking peptides of the present invention possess identical functions or activities to natural-occurring human EGF and are able to promote the generation of autocrine EGF in cells. In addition the peptides of the present invention are much higher stability and skin penetration potency than natural-occurring EGF. Therefore, the composition containing the peptide exhibits excellent treatment and prevention efficacies on diseases or conditions demanding EGF activities, and can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.
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申请公布号 |
US2010120696(A1) |
申请公布日期 |
2010.05.13 |
申请号 |
US20070444874 |
申请日期 |
2007.10.08 |
申请人 |
CAREGEN CO., LTD |
发明人 |
CHUNG YONG-JI;KIM YOUNG DEUG;KIM EUN MI;CHOI JUN YOUNG;SONG SANG SU |
分类号 |
A61K38/03;A61K8/64;A61P7/00;A61P17/00;A61P17/02;A61P25/00;A61Q19/00;C07K7/00 |
主分类号 |
A61K38/03 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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