发明名称 |
ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS |
摘要 |
The present invention provides low molecular weight porphyrin compositions for inhibiting, preventing or delaying the binding of a ligand of a mitochondrial benzodiazepine receptor. The invention also provides pharmaceutical compositions comprising these porphyrin compositions and their use in the treatment of conditions involving the mitochondrial benzodiazepine receptor or interactions between the receptor and the mitochondrial permeability transition pore e.g., drug overdose or apoptosis including neural degeneration and radiation-induced apoptosis.
|
申请公布号 |
US2010120738(A1) |
申请公布日期 |
2010.05.13 |
申请号 |
US20070440719 |
申请日期 |
2007.09.11 |
申请人 |
MALFROY-CAMINE BERNARD;DOCTROW SUSAN |
发明人 |
MALFROY-CAMINE BERNARD;DOCTROW SUSAN |
分类号 |
A61K31/555;A61P25/16;A61P25/28;C07D513/00 |
主分类号 |
A61K31/555 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|