摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide an instrument for performing remarkably and highly accurate PCR by using an assembly, a heated cover and an internal computer. <P>SOLUTION: The assembly is composed of a sample block (36), a number of Peltier thermal electric devices (39) and heat sink (34), all of which are clamped together. The temperature of the sample block (36) can be changed exclusively by a thermoelectric device (39) controlled by the computer. The sample block (36) is of low thermal mass and is made of silver. The Peltier devices are designed to provide fast temperature excursions over a wide range. The heat sink (34) has a perimeter trench (44) to minimize edge losses and is adjacent to a continuously variable fan. A perimeter heater is used to improve the thermal uniformity across the sample block (36) to approximately +/-0.2°C. <P>COPYRIGHT: (C)2010,JPO&INPIT</p> |