发明名称 |
COMPOSITION OF LABELED AND NON-LABELED MONOCLONAL ANTIBODIES |
摘要 |
This invention relates to a composition of labeled and non-labeled monoclonal antibodies directed to a human transmembrane protein for the simultaneous treatment and diagnosis of diseases which are associated with an overexpression of such a protein especially of cancer. The invention further relates to a method of first administering said composition, determine the change of labeled antibody concentration and afterwards administering the non-labeled monoclonal antibodies only such that the minimum required concentration of such non-labeled antibody for a favorable therapeutical effect is achieved and maintained in the treatment, while unfavorable side effects are minimized due to the lower systemic antibody concentration.
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申请公布号 |
US2010119457(A1) |
申请公布日期 |
2010.05.13 |
申请号 |
US20080593621 |
申请日期 |
2008.03.27 |
申请人 |
LENZ HELMUT;SCHEUER WEMER |
发明人 |
LENZ HELMUT;SCHEUER WEMER |
分类号 |
A61K49/00;A61P35/00 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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