MUCOSAL VACCINE USING CATIONIC NANOGEL

摘要

PROBLEM TO BE SOLVED: To provide a mucosal vaccine for oral or nasal administration that can induce an immunity response specific to a vaccine antigen in a living body without adding a mucous membrane adjuvant. SOLUTION: The mucosal vaccine preparation for preventing or curing an infectious disease caused by microbes to be administered through a mucous membrane contains a complex of the vaccine antigen and a nanogel formed by adding hydrophobic cholesterol as a side chain to a hydrophilic polysaccharide having a cationic functional group. COPYRIGHT: (C)2010,JPO&INPIT