发明名称 AGENT OF PROPHYLAXIS, THERAPY, AND OR SYMPTOM ALLEVIATION FOR PERIPHERAL NEUROPATHY RESULTING FROM CANCER CHEMOTHERAPY COMPRISING LIMAPROST
摘要 <P>PROBLEM TO BE SOLVED: To provide an agent of prophylaxis, therapy, and/or symptom alleviation for peripheral neuropathy resulting from cancer chemotherapy which is effective and safe, and can be orally administered. Ž<P>SOLUTION: Limaprosts of 15 μg or 30 μg by conversion to limaprost per day are orally administered for two weeks or 52 weeks, thereby numbness of four limbs, pain of four limbs, depletion of deep part tendon reflex, depletion of myodynamia, allodynia, hyperalgia, elaborate impairment of finger, gait disorder, false step, falling, flexing trouble (difficulty or impossibility of sitting up straight, sitting with one's legs crossed, horizontally sitting down, sitting down on a chair or the like), paralysis of four limbs or the like induced by cancer chemotherapy is improved. Therefore, limaprosts can be safe and effective agents of prophylaxis, therapy, and/or symptom alleviation for peripheral neuropathy resulting from cancer chemotherapy. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
申请公布号 JP2010106019(A) 申请公布日期 2010.05.13
申请号 JP20090229186 申请日期 2009.10.01
申请人 KANAZAWA UNIV;ONO PHARMACEUT CO LTD 发明人 NISHIMURA GENICHI;FUJITA HIDETO;NAKAO KENZO
分类号 A61K31/5575;A61P25/02 主分类号 A61K31/5575
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