发明名称 BENZOAZEPIN-OXY-ACETIC ACID DERIVATIVES AS PPAR-DELTA AGONISTS USED FOR THE INCREASE OF HDL-C, LOWER LDL-C AND LOWER CHOLESTEROL
摘要 The invention is directed to compounds of Formula (I) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertension, ischemia, stroke, irritable bowel disorder, inflammation, cataract, cardiovascular diseases, Metabolic X Syndrome, hyper-LDL-cholesterolemia, dyslipidemia (including hypertriglyceridemia, hypercholesterolemia, mixed hyperlipidemia, and hypo-HDL-cholesterolemia), atherosclerosis, obesity, and other disorders related to lipid metabolism and energy homeostasis complications thereof, using compounds of the invention are also described.
申请公布号 US2010120748(A1) 申请公布日期 2010.05.13
申请号 US20100689335 申请日期 2010.01.19
申请人 KUO GEE-HONG;ZHANG YAN;SHEN LAN;LU SONGFENG;DEMAREST KEITH T;PELTON PATRICIA 发明人 KUO GEE-HONG;ZHANG YAN;SHEN LAN;LU SONGFENG;DEMAREST KEITH T.;PELTON PATRICIA
分类号 A61K31/55;A61P3/04;A61P3/10;A61P7/00 主分类号 A61K31/55
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