发明名称 |
PRESERVATIVE SYSTEM FOR EMULSION-BASED THERAPEUTIC TOPICAL FORMULATIONS |
摘要 |
A topical formulation that inhibits the growth of microorganisms comprises an effective amount of an insecticide dissolved in an oil phase comprising a water-miscible or water-soluble surface active agent, a suspending agent, and a non-ionic surfactant, and an aqueous phase comprising one or more preservatives, where the aqueous phase is buffered to a specific pH. The overall antimicrobial efficacy in an emulsion formulation can be enhanced by buffering the aqueous phase of the emulsion to a pH at which the preservative system inhibits growth for a wider variety of microorganism types in the formulation relative to the equivalent formulation in which the aqueous phase is not buffered. |
申请公布号 |
WO2010051348(A1) |
申请公布日期 |
2010.05.06 |
申请号 |
WO2009US62500 |
申请日期 |
2009.10.29 |
申请人 |
TOPAZ PHARMACEUTICALS INC.;SPRING, NICHOLAS;DELANEY, EDWARD, J. |
发明人 |
SPRING, NICHOLAS;DELANEY, EDWARD, J. |
分类号 |
A01N25/00;A61K31/335;A61K31/70 |
主分类号 |
A01N25/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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