| 发明名称 |
CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF |
| 摘要 |
The present disclosure provides drug-ligand conjugates that are potent cytotoxins and include a linker between the drug and ligand where the linker has a single amino acid. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.
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| 申请公布号 |
US2010113476(A1) |
申请公布日期 |
2010.05.06 |
| 申请号 |
US20080528316 |
申请日期 |
2008.02.20 |
| 申请人 |
CHEN LIANG;GANGWAR SANJEEV;GUERLAVAIS VINCENT;LONBERG NILS;ZHANG QIAN |
发明人 |
CHEN LIANG;GANGWAR SANJEEV;GUERLAVAIS VINCENT;LONBERG NILS;ZHANG QIAN |
| 分类号 |
A61K31/496;A61K31/403;A61P35/00;C07D209/56;C07D403/02;C07K16/00;C12N5/00 |
主分类号 |
A61K31/496 |
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