IMPROVED METHODS OF USING PHOSPHOANTIGENS FOR THE TREATMENT OF DISEASES

摘要

The present invention provides novel approaches and strategies for efficient regulation of ?d T cells in vivo, in a subject, particularly a human subject or a non-human primate. The present invention now discloses particular compositions and methods that can be used to induce the activation of ?d T cells in vivo, in a subject. These compositions and methods employ the conjoint treatment of an individual with a ?d T cell activator and type I IFN and are particularly suited for immunotherapy in a subject, particularly in a subject having a cancer, an infectious or an autoimmune disease.