发明名称 |
Substituted Imidazole Derivatives, Compositions, and Methods of Use as PtPase Inhibitors |
摘要 |
The present invention provides imidazole derivatives of Formula (I-IV), methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I-IV), and their use in treating human or animal disorders. The compounds of the invention inhibit protein tyrosine phosphatase 1B and thus can be useful for the management, treatment, control, or the adjunct treatment of diseases mediated by PTPase activity. Such diseases include Type I diabetes and Type II diabetes.
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申请公布号 |
US2010113331(A1) |
申请公布日期 |
2010.05.06 |
申请号 |
US20100685178 |
申请日期 |
2010.01.11 |
申请人 |
TRANSTECH PHARMA, INC. |
发明人 |
MJALLI ADNAN M. M.;POLISETTI DHARMA R.;SUBRAMANIAN GOVINDAN;QUADA JAMES C.;YARRAGUNTA RAVINDRA R.;ANDREWS ROBERT C.;XIE RONGYUAN |
分类号 |
A61K31/433;A61K31/4439;A61K31/4545;A61K31/496;A61K31/501;A61K31/5377;A61K31/715;A61K38/28;A61P3/00;A61P3/10;A61P25/28;A61P35/00;A61P37/00 |
主分类号 |
A61K31/433 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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