| 发明名称 |
COMPOUNDS HAVING ANTI-ADHESIVE EFFECTS ON CANCER CELLS |
| 摘要 |
Compounds of the form O-(x-L)n, where O is an oligonucleoside having at least a plurality of N3′->P5′ thiophosphoramidate (NPS) internucleoside linkages, a conjugated lipid moiety L, and at least one G-rich sequence motif as described, are effective to morphologically alter and reduce adhesion of cancer cells.
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| 申请公布号 |
US2010113571(A1) |
申请公布日期 |
2010.05.06 |
| 申请号 |
US20080524844 |
申请日期 |
2008.01.30 |
| 申请人 |
GRYAZNOV SERGEI M;SHAY JERRY W;WRIGHT WOODRING |
发明人 |
GRYAZNOV SERGEI M.;SHAY JERRY W.;WRIGHT WOODRING |
| 分类号 |
A61K31/7088;C07H21/02;C12N5/02 |
主分类号 |
A61K31/7088 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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