发明名称 |
Screening Methods for Compounds that Modulate the Activity of G-Protein Coupled Receptors |
摘要 |
The present invention relates to a screening system for modulators of GPCRs. Further it relates to recombinant vector systems for the heterologous expression of heterodimeric g-protein coupled receptors (GPCRs) in eucaryotic host cells. Preferably the functional expression of engineered GPCRs for the perception of sweet and L-amino acid taste or more preferably the use of said receptors for the identification of functional ligands is also encompassed.
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申请公布号 |
US2010112688(A1) |
申请公布日期 |
2010.05.06 |
申请号 |
US20090616340 |
申请日期 |
2009.11.11 |
申请人 |
KROHN MICHAEL;ZINKE HOLGER |
发明人 |
KROHN MICHAEL;ZINKE HOLGER |
分类号 |
C12N5/10;C07H21/04;C12N15/00 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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