发明名称 Method and composition for inhibiting cardiovascular cell proliferation
摘要 Cardiovascular cell proliferation in a blood vessel subjected to trauma, such as angioplasty, vascular graft, anastomosis, or organ transplant, can be inhibited by contacting the vessel with a polymer consisting of from 6 to about 30 amino acid subunits, where at least 50% of the subunits are arginine, and the polymer contains at least six contiguous arginine subunits. Exemplary polymers for this purpose include arginine homopolymers 7 to 15 subunits in length.
申请公布号 US2010113353(A1) 申请公布日期 2010.05.06
申请号 US20090584609 申请日期 2009.09.08
申请人 LELAND STANFORD JUNIOR UNIVERSITY 发明人 COOKE JOHN P.;FATHMAN GARRISON C.;ROTHBARD JONATHAN B.;UEMURA SHIRO;ROBBINS ROBERT C.;KOWN MURRAY H.
分类号 A61K38/00;A61K38/16;A01N1/02;A61K38/03;A61K38/08;A61K38/10;A61L27/22;A61L27/34;A61L33/12;A61P7/04;A61P9/00;A61P9/14;A61P43/00;C07K2/00 主分类号 A61K38/00
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