发明名称 |
PHOSPHATIDYLINOSITOL 3 KINASE INHIBITORS |
摘要 |
Provided are compounds according to Formula (I), or stereoisomer, prodrug, polymorph, or pharmaceutically acceptable salt forms thereof, wherein X, Y, R1, R6 , R7, and R8 are as defined, which compounds are effective inhibitors of PI3-kinase and/or other medically and clinically relevant kinases. Also provided are pharmaceutical compositions and methods of using the compounds and compositions as PB -kinase and kinase inhibitors. More particularly, the compounds of the invention provide treatments and therapeutics for human diseases regulated by, or associated with, the activity of, PI3-kinases and/or protein kinases, or mutant or variant forms thereof.
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申请公布号 |
WO2009155527(A9) |
申请公布日期 |
2010.05.06 |
申请号 |
WO2009US47970 |
申请日期 |
2009.06.19 |
申请人 |
PROGENICS PHARMACEUTICALS, INC.;QIAN, DAPENG;HAN, AMY, QI;HAMILTON, MARK;WANG, ERIC |
发明人 |
QIAN, DAPENG;HAN, AMY, QI;HAMILTON, MARK;WANG, ERIC |
分类号 |
C07D487/04;A61K31/437;A61P35/00;C07D403/02;C07D487/02 |
主分类号 |
C07D487/04 |
代理机构 |
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地址 |
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