<p>Chimeric respiratory syncytial virus (RSV) polypeptide antigens are provided. The disclosed polypeptides include in an N-terminal to C-terminal direction: a first F protein polypeptide domain; a G protein polypeptide domain; and a second F protein polypeptide domain. The disclosure also provides nucleic acids that encode, and pharmaceutical compositions that contain, the chimeric RSV polypeptides, as well as methods for their production and use.</p>
申请公布号
EP2181121(A2)
申请公布日期
2010.05.05
申请号
EP20080751012
申请日期
2008.03.20
申请人
ID BIOMEDICAL CORPORATION OF QUEBEC
发明人
BLAIS, NORMAND;BURT, DAVID, S.;CYR, SONYA, L.;MARTIN, DENIS, L.;RHEAULT, PATRICK