| 发明名称 |
CXCR4 antagonists |
| 摘要 |
The present invention is drawn to novel antiviral compounds, pharmaceutical compositions and their use. More specifically this invention is drawn to derivatives of monocyclic polyamines which have activity in standard tests against HIV- or FIV-infected cells as well as other biological activity related to binding of ligands to chemokine receptors that mediate a number of mammalian embryonic developmental processes.
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| 申请公布号 |
US7709486(B2) |
申请公布日期 |
2010.05.04 |
| 申请号 |
US20080182044 |
申请日期 |
2008.07.29 |
| 申请人 |
GENZYME CORPORATION |
发明人 |
BRIDGER GARY J.;BOEHRINGER EVA MARIA;WANG ZHONGREN;SCHOLS DOMINIQUE;SKERLJ RENATO TONY;BOGUCKI DAVID EARL |
| 分类号 |
A61P19/02;A61K31/33;A61K31/381;A61K31/395;A61K31/4178;A61K31/4353;A61K31/44;A61K31/4427;A61K31/4433;A61K31/444;A61K31/496;A61K31/497;A61K31/52;A61K31/675;A61P1/00;A61P21/02;A61P25/00;A61P31/12;A61P31/18;A61P35/00;C07D257/02;C07D401/06;C07D401/12;C07D403/12;C07D409/12;C07D471/06;C07D471/08;C07D473/00;C07D487/08 |
主分类号 |
A61P19/02 |
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