发明名称 |
Methods for preventing or reducing ischemia/reperfusion induced myocardial cell death |
摘要 |
Provided herein are methods relating to inhibition of PUMA function for preventing or reducing myocardial cell death. A method for preventing or reducing ischemia/reperfusion induced myocardial cell death in a human is provided as are methods for identifying pharmaceuticals which interfere with PUMA function. Also herein provided is a method for reducing stem cell death in stem cell explants wherein the explants are intended to restore cardiac efficiency following cell death in response to coronary infarct.
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申请公布号 |
US7709216(B2) |
申请公布日期 |
2010.05.04 |
申请号 |
US20070891015 |
申请日期 |
2007.08.08 |
申请人 |
BOSTON BIOMEDICAL RESEARCH INSTITUTE |
发明人 |
ERHARDT PETER;TOTH AMBRUS |
分类号 |
A61K39/395;A61K48/00;C07K14/47;C12Q1/68;G01N33/74 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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