N-{(IS)-3-I3-isopropyl-5-metyl-4H-1,2,4-triasol-4-yl)-exo-8-azabicycklo[3.2.1]okt-8-yl]-1-fenylpropyl}-4,4-difluorcykloheksankarboksamid

摘要

The present invention provides compounds of the formula:
wherein R 1 is C 3-6 cycloalkyl optionally substituted by one or more fluorine atoms, or C 1-6 alkyl optionally substituted by one or more fluorine atoms, or C 3-6 cycloalkylmethyl optionally ring-substituted by one or more fluorine atoms; and
R 2 is phenyl optionally substituted by one or more fluorine atoms,
and pharmaceutically acceptable salts and solvates thereof; in combination with one or more additional therapeutic agents.