| 发明名称 |
IMPROVED PHARMACEUTICAL COMPOSITION CONTAINING DIHYDROPYRIDINE CALCIUM CHANNEL ANTAGONIST AND METHOD FOR THE PREPARATION THEREOF |
| 摘要 |
The present invention relates to the formulation of solid dosage forms comprising a therapeutically effective amount of a dihydropyridine calcium channel antagonist such as Lercanidipine or salt thereof, in combination with colloidal silicon dioxide such as Aerosilto enhance bioavailability and improve solubility, and a process for the preparation thereof by wet granulation.
|
| 申请公布号 |
KR20100045456(A) |
申请公布日期 |
2010.05.03 |
| 申请号 |
KR20107002430 |
申请日期 |
2008.07.23 |
| 申请人 |
PHARMATHEN S.A.;RECORDATI IRELAND LIMITED |
发明人 |
KARAVAS EVANGELOS;KOUTRIS MAKIS;SAMARA VICKY;MATSINGOU CHRISTINA;ILIOPOULOU ATHINA |
| 分类号 |
A61K31/4422;A61K9/20;A61P1/00;A61P25/00 |
主分类号 |
A61K31/4422 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
