| 发明名称 |
SUBSTITUTED AMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS |
| 摘要 |
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. |
| 申请公布号 |
EA013231(B1) |
申请公布日期 |
2010.04.30 |
| 申请号 |
EA20070002339 |
申请日期 |
2006.04.27 |
| 申请人 |
AMGEN INC. |
发明人 |
KIM TAE-SEONG;BAUER DAVID;BELLON STEVEN;BOERZIO ALESSANDRO;BOOKER SHON;CHOQUETTE DEBORAH;D'AMICO DERIN, C.;D'ANGELO NOEL;DOMINGUEZ CRLIA;FELLOWS INGRID, M.;GERMAIN JULIE;GRACEFFA RASSELL;HARMANGE JEAN-CHRISTOPHE;HIRAI SATOKO;LA DANIEL;LEE MATTHEW;LIU LONGBIN;NORMAN MARK, H.;POTASHMAN MICHELE;POVETO PHILIP;SIEGMUND AARON, C.;XI NING;YANG KEVIN |
| 分类号 |
C07D401/14;A61K31/435;A61K31/495;A61P35/00;C07D401/12;C07D403/12;C07D405/14;C07D409/14;C07D413/12;C07D413/14;C07D417/14;C07D487/04;C07D495/04 |
主分类号 |
C07D401/14 |
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