| 摘要 |
PURPOSE: A manufacturing method of enteric choline chloride and the choline chloride manufactured thereby are provided to manufacture the enteric choline chloride of high choline content, and to improve working efficiency by circulating an operation process. CONSTITUTION: A manufacturing method of enteric choline chloride includes a step for manufacturing granules(2) by processing choline chloride with a binder and a step for coating granules with one or more coating agent. A reactor is a fluidized bed granulator. The fluidized bed granulator is processed the binder or the coating agent with a bottom spray mode. The binder is polyvinyl acetate, polyvinyl alcohol, polyacrylic acid, polymethacrylic acid, polyvinylpyrrolidone, glucose, sucrose, lactose, maltose, sorbitol, mannitol, hydroxyethyl cellulose, hydroxypropyl cellulose, polyethylene glycol, methyl methacrylate, or a mixing agent of polyvinylacetate and povidone etc. |
